medspa mastery logoSubscribe to The Medspa Mastery Report: The Go-To Hub for News, Tools, and Growth in the Aesthetic Industry.

🚨 Nordstrom partners with SkinSpirit for medspa services | 💡 Empower Aesthetics announces partnerships with Livio Medspa and Georgous Aesthetics Bar | 🛑 Eli Lilly sues Colorado Medspa, Thrive Health and Wellness, for selling trizepatide | Journey Medical's Emrosi Rosacea Pill Receives FDA Approval | ⚕️ Hippocratic AI gets 141M in Series B funding | 💡 Texas Bills HB 3567 and SB 1700 could reshape APRN roles in medspas—stay informed on regulatory changes impacting operations | 🛑 Eli Lilly sues NY Medspa, Valhalla Vitality, for selling trizepatide | 🟤 Mocha Mousse Chosen as 2025 Pantone Color of the Year | 🚨 Journey Medical's Emrosi Rosacea Pill Receives FDA Approval | ❗️Supreme Court appears likely to uphold impending Tik Tok ban | 💡 Partnerships show medspa consolidation trend | ⚕️ Hippocratic AI gets 141M in Series B funding | 🟤 Texas Bills HB 3567 and SB 1700 could reshape APRN roles in medspas—stay informed on regulatory changes impacting operations| 💉 Microdosing Semaglutide, the newest trend |

The Skincare Ingredient Everyone’s Talking About

Salmon DNA, also known as polydeoxyribonucleotides (PDRN), has been generating buzz in the skincare world for the past couple of years – and since it appears to be a trend that is not going way, we are going to break it all down for you.

While the term “salmon sperm DNA” sounds like a marketing tactic, it actually does refer to the DNA extracted from salmon sperm, celebrated for its regenerative properties. This ingredient has been making waves globally, especially in South Korea, where it’s used in injectables, topical serums, and even microneedling treatments.

In regions like Europe and Australia, medspas are already embracing salmon DNA as part of their skincare offerings, earning rave reviews for its ability to promote skin healing, boost collagen, and enhance hydration. But what about medspas in the U.S.? Let’s dive into the possibilities and limitations.

The Status in the U.S.: Legal Considerations

The U.S. Food and Drug Administration (FDA) has yet to approve injectable salmon DNA treatments, meaning medspas cannot offer this in injectable form.

However, topical products containing salmon DNA are available and can be safely and legally integrated into procedures like microneedling.

Clarification About the Term:
“Salmon sperm DNA” sounds unconventional, but it refers to the extracted DNA, not an active component of sperm. It’s a highly refined ingredient used to stimulate skin repair and rejuvenation.

If you’re a medspa owner in the U.S., sticking to topical applications during microneedling sessions allows you to provide innovative treatments while staying compliant with regulations.

young girl with blue eyes and freckles looking straight ahead

Is Salmon DNA Is Better Than Traditional Methods (when added to Microneedling Treatments?)

Adding salmon DNA to microneedling offers advantages over standard microneedling alone:

  1. Enhanced Skin Regeneration
    PDRN promotes cellular repair and tissue growth, accelerating skin recovery and delivering a smoother texture. (Read more)
  2. Boosted Collagen Production
    Salmon DNA amplifies collagen synthesis, leading to firmer, more elastic skin.
  3. Superior Hydration
    The deeply hydrating properties of PDRN help the skin achieve a radiant glow. 
  4. Anti-Inflammatory Benefits
    Salmon DNA reduces inflammation, which can enhance recovery after microneedling treatments.
manhattan medpa offering

Medspas Leading the Way

Several medspas in the U.S. have already embraced salmon DNA in their treatments:

These examples demonstrate the growing adoption of this innovative treatment, even in a more regulated market like the U.S.


How to Incorporate Salmon DNA Into Your Offerings

Here’s how to get started:

 

  1. Source Reliable Products
    • Rejuran USA: Offers topical PDRN-based serums.
    • PDO Max LúmEnvy™: A skincare solution blending salmon DNA with other active ingredients.
    • Explore Korean skincare marketplaces like YesStyle for additional options.
  2. Update Your Treatment Protocols
    Add salmon DNA serums during microneedling to enhance results without requiring injectables.
  3. Educate Your Team
    Train your staff on the science behind salmon DNA and how to discuss its benefits with clients confidently.

Marketing and Promoting the Trend

Here’s how to make a splash with your new offering:

  • Educate Your Clients
    Share blog posts, social media updates, or in-spa materials explaining the benefits of salmon DNA treatments.
  • Create Packages
    Launch treatments like “The Korean Glow Package,” featuring microneedling with salmon DNA infusion.
  • Leverage Trends
    Highlight the global popularity of Korean skincare and its reputation for innovation and effectiveness.
  • Show Results
    Use before-and-after photos and testimonials to showcase the benefits of salmon DNA.

Should You Add Salmon DNA to Your Medspa?

Yes, yes you should.

Especially, if you’re looking to stay on the cutting edge of skincare trends, meet client demand, and deliver enhanced results.

Salmon DNA offers a powerful way to differentiate your medspa while providing a treatment that aligns with science and client expectations. With proper sourcing, compliance, and creative marketing, it’s a trend that could set your business apart.