A new case study published in Cureus by Saami Khalifian, MD; Alec D. McCarthy, MD; and Steven Yoelin, MD, examines the efficacy and safety of an injectable therapy for treating neck wrinkles and skin laxity. This therapy combines hyperdiluted calcium hydroxylapatite (CaHA), platelet-rich plasma (PRP), and hyaluronidase.

Two patients with moderate neck wrinkles and skin laxity received the treatment and were evaluated several months later.

The study found that a single treatment with the combined therapy improved skin texture and laxity.

The inclusion of PRP and hyaluronidase aimed to enhance the regenerative effects of CaHA. PRP is rich in growth factors that stimulate collagen production and regeneration, while hyaluronidase breaks down hyaluronic acid, promoting better diffusion and even product dispersion.

The findings from these cases provide preliminary evidence supporting the safety and efficacy of this innovative combination therapy for addressing neck wrinkles and laxity.

According to the researchers, this is the first documented instance of using CaHA in conjunction with hyaluronidase and PRP for skin priming.

Further investigations are needed to explore the application of this treatment for other anatomical regions and to clarify the role of each injected component.

Read complete findings at Cureus