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Best Neuromodulator 2025: Compare Botox, Daxxify, Juveau, Xeomin & Letybo

Medical Spa injectors all have their favorites, but if you are new to the industry or are considering adding Letybo to your neuromodulator offerings, then understanding the ROI associated with each market wrinkle reducer is key for growth. So, in honor of the Letybo launch we broke it down for you – and included a little calculator to help you as well.

Botox vs Daxxify vs Juveau vs Xeomin vs Letybo vs Dysport: A Side-by-Side Comparison

The wholesales price per vials are as of February 2025 AND are not $$ exact as the cost varies based upon volume ordered. A new business will pay more than an established medspa ordering large volumes.

Neuromodulator Comparison Chart

Neuromodulator Duration Units Per Vial Wholesale Price Per Vial Cost Per Unit for Provider
Botox 3-4 months 100 units $600-$700 $6-$7
Daxxify 6+ months 50 units $400-$500 $8-$10
Juveau 3-4 months 100 units $300-$400 $3-$4
Xeomin 3-4 months 100 units $400-$500 $4-$5
Letybo 3-4 months 100 units $400-$500 $4-$5
Dysport 3-4 months 500 units $300-$500 $0.60-$1.00

Considerations beyond price:

  • Botox is trusted and widely recognized. Love it or hate it, their Alle program is a favorite of clients.Ā 
  • Daxxify offers longer-lasting effects and does not require refrigeration.
  • Juveau is budget-friendly and effective.
  • Xeomin is a “pure” formulation with no complexing proteins, reducing the risk of antibody formation
  • Letybo , the newest FDA-approved neuromodulator, is already a top choice in South Korea and is gaining traction in the U.S. for its fast-acting results and smooth finish.

How Much Should You Charge for Neuromodulators?

Determining the right price for neuromodulator treatments is key to maximizing ROI. Our free ROI calculator can help you calculate profitability based on your wholesale costs and retail pricing.

    Neuromodulator ROI Calculator

    Cost Per Unit: $0.00

    Profit Per Unit: $0.00

    Total Profit Per Vial: $0.00

    FAQs About Neuromodulators

    Q: Which is the best neuromodulator for my medspa?

    • A: The best neuromodulator depends on your goals. Botox is trusted and widely recognized, while Daxxify offers longer-lasting effects. Letybo, the newest option, is gaining popularity for its fast-acting results.

    Q: How much should I charge for Botox?

    • A: Pricing varies by location and demand, but the average cost per unit is $10–$15. Use our ROI calculator to find the optimal price for your business.

    Q: What is the difference between Botox and Letybo?

    • A: While both are neuromodulators, Letybo is newer to the U.S. market and is known for its fast-acting results and smooth finish. Botox, on the other hand, has decades of proven effectiveness and brand recognition.

    If you are a U.S. based Medspa interested in adding Letybo, you can connect with them here.

    letybo in the united states